The family of NMDA enzyme antagonists

Generic name: Amantadine

Commercial name: PK Merz, Paritrel 

  • A drug that stimulates the release of dopamine.
  • It is usually given in the early stages of the disease or in combination with an anticholinergic drug or levodopa.
  • The treatment can be given intravenously in a hospital or day hospital over several consecutive days.

Advantages

May reduce levodopa-related dyskinesias.

Disadvantages

After several months, the effect of Amantadine wears off in half or a third of the patients who use it. Its effect can return after taking a short break from the drug.

Side Effects

 Mottled skin, edema of the legs, dry mouth, confusion, blurred vision and depression.

Click here to view the circular of the Ministry of Health from the website "All Health" - pk merz

Click here to review the Ministry of Health's circular from the "All Health" website - paritrel

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